Quantifying Hepatitis B and C Burden in Asia
Viral hepatitis continues to be one of the deadliest infections in the world, attributed as the cause of one death every 25 seconds, as well as being identified as the leading cause of liver cancer in the world. Most cases of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are in Asia, so it is important to quantify the disease burden in Asia to help international agencies, public health organizations and policy-makers develop strategies to eliminate these infections.
Today, there are many treatments to eliminate viral hepatitis. With the availability of vaccines that can effectively prevent Hepatitis B, many countries have adopted large-scale vaccination practices for infants, one such example being China. Treatment for Hepatitis B has also been developed for patients who had been infected prior to the availability of vaccines, and existing treatments for Hepatitis C can cure patients within the span of 12 weeks. However, many cases of HBV and HCV still remain untreated to this day.
Since 2018, the ZeShan Foundation has been providing funding to the Center for Disease Analysis Foundation in their efforts to help countries in Asia eliminate hepatitis B and C in the region. To study and publish a report on the breadth of hepatitis B and C burden across Asia, the CDA Foundation worked closely with Asian countries to collect data on the number of people infected, diagnosed, and treated. In this project, mathematical models were used to estimate the impact of viral hepatitis in Asia, the summary of which is shown below. From the data collected, an estimate of 188 million people in Asia are infected with hepatitis B (Figure 1) and another 34 million with hepatitis C (Figure 2). For more details, please view the CDA Foundation’s website: https://cdafound.org/dashboard/polaris/dashboard.html.
The compiled research reveals that a majority of global HBV- and HCV-related cases of liver cancer and liver related deaths are concentrated in Asia (Figure 3). This analysis will help Asian countries obtain more funding for the elimination of viral hepatitis, and additionally recruit support from their government to test and treat this population through HBV vaccinations.
Fig. 1 An estimate 188 million people in Asia were infected with hepatitis B
Fig. 2 34 million people in Asia were infected with hepatitis C
Fig. 3 A majority of global HBV- and HCV-related cases of liver cancer and liver related deaths are concentrated in Asia
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